Science & Math | Scientific Reference

A Handbook for DNA-Encoded Chemistry

by Robert A. Goodnow

2020-04-16 17:36:29

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This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation t... Read more

This book comprehensively describes the development and practice of DNA-encoded library synthesis technology. Together, the chapters detail an approach to drug discovery that offers an attractive addition to the portfolio of existing hit generation technologies such as high-throughput screening, structure-based drug discovery and fragment-based screening. The book:

  • Provides a valuable guide for understanding and applying DNA-encoded combinatorial chemistry
  • Helps chemists generate and screen novel chemical libraries of large size and quality
  • Bridges interdisciplinary areas of DNA-encoded combinatorial chemistry – synthetic and analytical chemistry, molecular biology, informatics, and biochemistry
  • Shows medicinal and pharmaceutical chemists how to efficiently broaden available “chemical space” for drug discovery
  • Provides expert and up-to-date summary of reported literature for DNA-encoded and DNA-directed chemistry technology and methods
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Book Details

Publication date March 28, 2014
Languageeng
ISBN9781118832691
autor-image
Robert A. Goodnow
Author
ROBERT A. GOODNOW, JR. is the Executive Director of the Chemistry Innovation Centre, Discovery Sciences at AstraZeneca and the Founder of GoodChem Consulting, LLC. He has extensive experience in drug ...

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