Biomarkers in Drug Discovery and Development
by Ramin Rahbari
2020-07-23 01:11:39
Biomarkers in Drug Discovery and Development
by Ramin Rahbari
2020-07-23 01:11:39
This book continues the legacy of a well-established reference within the pharmaceutical industry â providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker ch...
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This book continues the legacy of a well-established reference within the pharmaceutical industry â providing perspective, covering recent developments in technologies that have enabled the expanded use of biomarkers, and discussing biomarker characterization and validation and applications throughout drug discovery and development. ⢠Explains where proper use of biomarkers can substantively impact drug development timelines and costs, enable selection of better compounds and reduce late stage attrition, and facilitate personalized medicine⢠Helps readers get a better understanding of biomarkers and how to use them, for example which are accepted by regulators and which still non-validated and exploratory⢠Updates developments in genomic sequencing, and application of large data sets into pre-clinical and clinical testing; and adds new material on data mining, economics, and decision making, personal genetic tools, and wearable monitoring⢠Includes case studies of biomarkers that have helped and hindered decision making⢠Reviews of the first edition: âIf you are interested in biomarkers, and it is difficult to imagine anyone reading this who wouldn't be, then this book is for you." (ISSX) and ââ¦provides a good introduction for those new to the area, and yet it can also serve as a detailed reference manual for those practically involved in biomarker implementation.â (ChemMedChem)
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