Biometals in Autism Spectrum Disorders

Biometals in Autism Spectrum Disorderswill be the first to focus on trace metals and autism. Compared to other references examining ASDs or metallomics, a focused presentation of the findings of abnormal metal homeostasis in ASD has not yet come to be. This book provides for readers an overview of current findings on trace metal biology with respect to its role in ASD etiology and discusses how abnormal trace metal biology may be a common factor of several genetic and non-genetic causes of ASDs considered unrelated in the past. This will open new vistas for the development of new therapies based on targeted manipulation of trace metal homeostasis and generate awareness that trace metal levels during pregnancy must be tightly monitored.

• Reviews the role of trace metals in brain development
• Summarizes research linking trace metals and autism
• Explores heterogenous phenotypes as a factor of genetic and non-genetic factors
• Includes animal and human stem research
• Contains many diagrams, tables, and flow charts
• Proposes future therapies based on biometal homeostasis