Developability of Biotherapeutics

Biopharmaceuticals emerge as frontline medicines to fight a number of life-threatening and chronic diseases. They are currently the fastest growing pharmaceutical group, being a treatment option for a variety of chronic and life-threatening condition... Read more

Biopharmaceuticals emerge as frontline medicines to fight a number of life-threatening and chronic diseases. They are currently the fastest growing pharmaceutical group, being a treatment option for a variety of chronic and life-threatening conditions. A variety of natural products covering nucleic acids, viral particles, whole cells, proteins and vaccines are represented by biotherapy. Recently, major steps have been taken to develop safer and more efficient biotherapeutics and to adopt cost-effective, efficient and streamlined production processes. In the coming years, this trend is likely to accelerate as emerging areas relating to advanced therapies or even personalized medicine mature. In spite of these advances, you can find knowledge gaps at all stages of development, together with regulatory and technical obstacles that could stop the approval process for these items. A group of topics covering relevant biotherapeutics aspects are presented in this title. This compilation describes the application of computer and molecular modeling techniques that improve the overall discovery and development process by eliminating empiricism. This book collectively gives a comprehensive overview of the current advances in biotherapy and the exciting challenges ahead. It should be of a valuable tool for industry research and development professionals, practitioners, scientists working with regulatory agencies and students and educators in pharmacy, medicine and life sciences. Less